Common Clinical Phenomenon Of Irrational Use Of Antibiotics – Antibiotics – The Pharmaceutical

Antibiotics are the most widely used clinical types of drug, one of the increasing frequency of its use in recent years, the use range is also expanding and improving pharmaceutical grade, in the prevention and treatment of infections play an important role, but there are some unreasonable drug problems, now common clinical use of antimicrobial drugs is unreasonable for the analysis:

Case 1: No indication of drug use

Patients Ryu, M, 42 years old, bus drivers, recent headache, fever, sore throat, the doctor Cephalosporin Risperidone intravenously, 3 days without any improvement, then disable cefoperazone plus anti-virus oral solution, a 20 ml (2), before breakfast, lunch or dinner after the taking; oral Chaihuang particles, once a bag, twice a day, for 3 days after the fever subsided, five days after the throat pain relief, a Zhouhou Kang Fu.

Futurist of the patients develop fever, headache, sore throat, are typical symptoms of upper respiratory tract infection, and mostly viral infection, antimicrobial drug use did not sign, the use of cefoperazone is irrational drug use. Later use of antiviral drugs from the effects of view, it is infected, it would be inappropriate use of antibiotics.

Case 2: drug overdose Patients Tianmou, F, 28 years old, a middle school math teacher, a full-term baby, cesarean section, use Cefamandole 3.0 g, twice a day, added 0.9% sodium chloride injection intravenously.

Futurist cesarean section the patient belongs to a class of incision, you can not use antibiotics. If used, should be low-dose, short-term use, the case of the first use of Cefamandole 3.0 grams, is a serious drug overdose, general infection with 1.0 to 1.5 g can be a serious infection can be increased to 2.0 grams.

Case 3: no indication of joint use of drugs

Patients with the surname of Huang, M, 49 years old, farmers, recent cough, sputum, fever, intravenous antibiotics in the clinic, the effect of poor hospital treatment to hospital. Diagnosis of acute pneumonia, the doctor medication as: cefodizime 1.5 g, 0.9% sodium chloride added to the intravenous injection, 0.4 g of levofloxacin injection, intravenous drip, once a day.

Futurist cefodizime the patient and the use of levofloxacin in combination, there is no indication of drugs, mostly pneumonia, Gram-negative bacterial infections, third generation cephalosporin good cefodizime its efficacy, general alone This can be a drug for therapeutic purposes, without the joint use of antimicrobial agents, except mixed infection or drug-resistant infections.

Case 4: ignoring contraindications drugs Patient Shen, M, 67 years old, retired cadres, chronic prostatitis, bacterial cultures showed amikacin sulfate, cefoperazone, levofloxacin-sensitive, and resistant to other drugs. Medical use of amikacin sulfate 0.4 g once a day, once added to the 0.9% sodium chloride injection in intravenous therapy.

Futurist of the patients are elderly patients, while for amikacin sulfate sensitive, but because of the existence of renal dysfunction, creatinine and blood urea nitrogen significantly higher, contraindications to the drug. Select the same sensitive levofloxacin or cefoperazone-pin, can also play applied to the treatment, the case with classic contraindications to ignore the irrational drug use.

Case 5: Incompatibility Were Lee, M, 66 years old, retired workers in a coal mine, 5 days ago left leg fracture, hospital treatment, recent cough, asthma. Medication after the operation were: ciprofloxacin injection, a 0.2 g twice a day. Use of aminophylline needle, a 0.5 g, twice a day, adding to the 0.9% sodium chloride injection intravenously.

Futurist with the use of ciprofloxacin and theophylline, aminophylline and ciprofloxacin can significantly reduce the rate of liver clearance, clearance half-life extension of plasma concentration, appears related to theophylline poisoning symptoms such as nausea, vomiting, tremor, anxiety, agitation, palpitations, etc., generally not compatible uses. Must be used, it should be timely monitoring of blood concentration of theophylline.

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